MAS-100 Sirius®
Next-generation active microbial air sampler
Reference reloaded: MAS-100 Sirius® is the successor of the MAS-100 NT® – the world’s best-selling active air sampler. The agar-based sampler sets a new standard in monitoring microbial air contamination. Engineered to achieve highest precision and to minimize the risk of secondary contamination, it is ideally suited for both non-controlled and controlled environments such as pharmaceutical cleanrooms.
Listened. Understood. Evolved.
Automated instrument checks inform operators about missing or incorrect components during the measurement and assure fast detection of operational errors. A leak test verifies the proper contact of the perforated lid. Calibration of both flow and timer are traceable, sensor drifts are identified at an early stage thanks to the dual-sensor design of MAS-100 Sirius.
The seamless stainless steel design allows for easy cleaning of the instrument. The innovative magnetic lid with handle helps to ensure aseptic operation, as it keeps the operators’ hands out of the critical measurement zone. The inner path of the device head can be actively decontaminated with VHP.
MAS-100 Sirius includes a complete and tamper-evident audit trail with convenient live filtering. Thanks to the sampling data export via a result barcode or WiFi, data integrity is assured. In case of deviations, errors are logged in the audit trail based on pre-defined sampling error reasons on the display. With the optionally included user management, access can be precisely controlled.
With its lean user interface and simple navigation, the configurable one-button sampler clearly guides users through the process and reduces the risk of operating errors – just as the easy-to-use magnetic lid with handle does. The plate holder can be adjusted for 55 mm and 90 mm agar plates as well as Growth Direct® cassettes without additional tools. On top of that, the measuring time is significantly reduced thanks to the high flow rate of 200 SLPM, to ensure tight schedules can be met.
KEY FEATURES OF MAS-100 SIRIUS
Flexible agar plate holder
Time-saving and tool-free adjustment for the use of 55mm and 90mm plates as well as GrowthDirect® cassettes without additional adapter.
Seamless stainless-steel design
Smooth material without dirt traps for easy disinfection.
Large user interface with tactile button
Customizable one-button sampler with simplified and intuitive user navigation to prevent clicking errors.
Magnetic lid with handle
Self-aligning lid without polymer ring avoids risk of jamming and requires less force to open.
ISO 35H / HEPA H13 exhaust filter
User-exchangeable filter including touching protection for assured integrity, traceable with batch certificate.
Wide instrument base
For a stable stand, expandable with tripod. With user-replaceable battery, USB-C and optional WIFI connection
WHAT'S IN FOR YOU?
Next-level aseptic sampling, developed with your feedback:
- Magnetic lid with handle – aseptic and easy operation, with every sampling, again and again
- Streamlined OR Clean and intuitive user interface design – easy to learn, effortless to use
- One-button sampler – fast sampling with just 2 clicks
- Automated instrument self checks – instant detection and response to issues
- Seamless stainless steel design – no more dirt traps
Confidence in every sample:
- Customizable simple one-button or multi-option sampler - TBD
- Sealing integrity check – detect and replace damaged lids early
- Error-proof data transfer via barcode or WiFi – full data integrity
- User-replaceable battery and filter – uninterrupted efficiency
Compliance with ISO 14698 / EN 17141, GMP Annex 1 and 21 CFR part 11:
- Dual-sensor technology – best in class reliability
- Complete and tamper-evident audit trail – full traceability
- 21 CFR part 11 compliant user management – secure access control
- Lid with handle and seamless stainless steel design – lower risk of secondary contaminations
Ready to explore?
SERIOUS AIR SAMPLING
Safe, aseptic handling
The magnetic lid with handle is a world first. The angled, ergonomic grip greatly simplifies handling during sampling. The result: less needed force, no risk of jamming, and contamination-free operation from the side. Like the entire instrument body, it is made of stainless steel.
Intuitive operation
Operator confusion due to a large number of options is a thing of the past. The configurable one-button sampler clearly guides through the sampling process: Its uncrowded user interface is reduced to the essentials and comes with large fonts as well as clear color schemes. This significantly diminishes operating errors and speeds up the measurement.
Product essentials
Material
316L stainless steel (body and perforated lid)
Dimensions
277x147x160mm (HxWxD, incl. lid and handle)
Weight
2.6kg (with lid)
Plate compatibility
90 mm standard and 55 mm contact plates, Growth Direct® cassettes
Air flow rate and accuracy
100 and 200 standard liters per minute (SLPM), ± 2.5 %
Air volume
Freely selectable collection volume between 50 and 4000 SL
Physical cut off diameter
d50 ≥ 1.1 µm (according to ISO 14698 / EN 17141) depending on combination of lid and flow rate used
Battery
At least 30 sampling cycles of 100L at 100 SLPM without recharging
Browser-based user interface
For configuration, calibration and audit trail access (no internet or software needed)
Configurable sampling configurable
With one-button or multi-parameter selection
Optional local user management
With segregated user roles or active directory login in accordance with 21 CFR Part 11
Tamper-evident audit trail
With filter function
Optional sampling data export
Using result QR code or wireless connection
Automatic calibration
Of air flow (with MAS-100 Regulus®) and timer (wireless connection to network time protocol server)
MAS-100 Sirius has been developed according to ISPE GAMP5 and is fully validated as per PDA TR #13, EU GMP Annex 1, as well as ISO 14698 / EN 17141:
- Volume accuracy assured within narrow tolerance of +/- 2.5%
- Validated physical and biological sampling efficiency at 100 and 200 SLPM
- No disturbance of laminar air flow
- Particle emission compliant to GMP Grade A
- Proven resistance to standard disinfectants incl. sporicidals and VHP
- Traceable air flow and timer calibration
- Successful 21 CFR Part 11 and GMP Annex 1 certification
- Secure electronic records and data integrity
MAS-100 Sirius microbial air sampler
USB-C communication and charging cable with region-specific adapters
Transport case
Standard package:
- Perforated lid type A (300x0.6mm for 90mm plates
- Dust lid
- Calibration certificates for 100 SLPM with lid type A (300x0.6mm), 100 SLPM with lid type B (400x0.7mm) and 200 SLPM with lid type B
Flex package:
- Blind lid
- Calibration certificates for 100 SLPM with lid type A (300x0.6mm), 100 SLPM with lid type B (400x0.7mm) and 200 SLPM with lid type B
As your partner in microbial air monitoring, our service team supports you throughout the entire product lifecycle. Whether it's calibration, adjustment, application support, or repair – we are committed to delivering the highest quality and ensuring your satisfaction.
MAS-100 Sirius
Proven impaction technology
For active microbial air sampling based on the impaction principle, a predefined volume of air is drawn through a perforated sieve. The air and the particles in it are accelerated and directed onto an agar plate positioned below the sieve.
Due to inertia, particles above a certain size are impacted onto the agar medium. After appropriate incubation, microbe-bearing particles become visible as colony forming units (CFU), can be counted and reported as CFU/m3. The particle size at which 50% of the particles impact and the other half remain in the air stream is called the cut off diameter d50 (um).
Great emphasis is placed on precision in the manufacture of MBV perforated sieves. This ensures that the cut off diameter is identical in all holes and that microbial air sampling is repeatable.
Both the comparison of several MAS-100 Sirius instruments and the comparison of different perforated covers of the same type confirmed the consistent performance in practice.
FAQ
Yes, the audit trail of MAS-100 Sirius display as well as the exported XML file is tamper-proof. In addition the instrument features a file integrity check in order to identify if the exported file had been modified or corrupted since its export. This makes the exported files tamper-evident. To prevent from unintended data loss, deletion of the audit trail is only possible after a successful export.
Yes, MAS-100 Sirius is compatible with LIMS systems. Integration can be achieved in two ways: by scanning the sampling result QR code displayed on the instrument, or via wireless connection using a RESTful API interface.
MAS-100 Sirius includes an integrated leakage test, which can be accessed via the local user interface. MBV recommends incorporating this test into your standard operating procedures (SOPs) and performing it regularly. By doing so, potential tightness issues can be detected early, helping to prevent problems that may lead to OOS results during as-found calibrations. Furthermore the instruments contains dual sensor allowing identification of sensor drifts early.
Want to dive deeper? Our full FAQ section covers many more questions about the MAS-100 Sirius’s features, usage, and support. Take a look — the answer you’re looking for might already be there!
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